Composition containing 4-oxovaleric acid and leuconostoc/radish root ferment filtrat

ABSTRACT

A composition comprising 4-oxovaleric acid present in an amount of 0.05 to 1% by weight (as supplied) of the composition and  leuconostoc /radish root ferment filtrate present at 0.2 to 2% by weight (as supplied) of the composition.

CROSS REFERENCE TO RELATED APPLICATIONS

This application is a divisional application of application Ser. No.13/810,851 filed on 17 Jan. 2013, which is a national stage entry ofPCT/US2010/042409, filed on 19 Jul. 2010, all of which are incorporatedherein by reference.

BACKGROUND

For consumers who use liquid cleansing compositions, such as showergels, body washes, or liquid hand soaps, foaming of the cleansingcomposition during use is desired. Also, it is desired to provide asufficient amount of foam that is stable for a desired amount of timeduring use. Also, there is a desire for the foam to provide a creamytexture. The foam volume and creaminess usually compete against eachother. As one is increased, the other one usually decreases. It isdesired to provide a cleansing composition with a desired amount of foamand a desired amount of creaminess.

BRIEF SUMMARY

A composition comprising 4-oxovaleric acid present in an amount of 0.05to 1% by weight (as supplied) of the composition and leuconostoc/radishroot, ferment filtrate present at 0.2 to 2% by weight (as supplied) ofthe composition.

DETAILED DESCRIPTION

As used throughout, ranges are used as a shorthand for describing eachand every value that is within the range. Any value within the range canbe selected as the terminus of the range. In addition, all referencescited herein are hereby incorporated by reference in their entireties.In the event of a conflict in a definition in the present disclosure andthat of a cited reference, the present disclosure controls.

Unless otherwise specified, all percentages and amounts expressed hereinand elsewhere in the specification should be understood to refer topercentages by weight. The amounts given are based on the active weightof the material.

Typically, anionic surfactants are used to provide foamingcharacteristics to compositions. Other types of surfactants may notgenerate as much or the same quality of foam as does anionicsurfactants. It is been discovered that a combination of decyl and cocoglucosides can provide foaming that is comparable to anionicsurfactants. In certain embodiments, anionic surfactants can beeliminated from the composition, but the composition can still have adesired level of foaming.

A cleansing composition that includes surfactants comprising decylglucoside and coco glucoside, wherein the amount of decyl glucoside is1.5 to 2.5, 1.8 to 2.2, or 1.9 to 2.1 times the amount of coco glucosideby weight. In certain embodiments, the amount of decyl glucoside isabout 2 times the amount of coco glucoside.

The decyl glucoside and the coco glucoside can be included in thecomposition in any amount as long, as the weight ratio is maintained. Incertain embodiments, the amount of decyl glucoside is 1 to 30 weight %,1 to 20 weight %, or 10 to 20 weight % of the composition. In certainembodiments, the amount of decyl glucoside is 20, 15, or 10 weight %. Incertain embodiments, the amount of coco glucoside is 0.5 to 20 weight %,0.5 to 10 weight % or 5 to 10 weight % of the composition. In certainembodiments, the amount of coco glucoside is 10, 7.5, or 5 weight %.

The decyl and coco glucoside surfactants can be obtained from CognisCorporation. The coco glucoside is sold as Plantacare™ 818 UP. The decylglucoside is sold as Plantaren™ 2000 N UP.

In certain embodiments, the cleansing composition can contain athickener. Examples of the thickener include, but are not limited toxanthan gum, konjac mannan, gellan gum, carrageenan, carboxymethylcellulose, guar gum, rhamsan gum, furcelloran gum, celluloses,polysaccharides, pectin, alginate, and arabinogalactan. In oneembodiment, the thickener is xanthan gum. In another embodiment, thethickener is kontac mamma. In certain embodiments, the thickener ispresent in an amount alone or in combination of 0.1 to 5% by weight,0.25 to 2% by weight, 0.75 to 1.5 by weight, or 1 to 1.25% by weight.

The cleansing composition contains water. Water can be present in anydesired amount of the cleansing composition to form a typical cleansingcomposition, such as it shower gel, a body wash, liquid hand soap, orfoaming hand soap.

The cleansing composition can contain additional surfactants. In certainembodiments, the surfactants can consist essentially of the decyl andcoco glucosides, or the surfactants can consist of the decyl and cocoglucosides. In certain embodiments, the total amount of surfactant canbe 1 to 45% by weight of the composition.

Additionally, the cleansing composition can contain any other materialsthat can be included in a cleansing composition. Examples of additionalsurfactants and other materials can be found in United States PatentPublication No. 20070048235. The pH of the composition can be adjustedwith citric acid.

In the examples below, the compositions contain a combination ofDermosoft™ 700B perfume and Leucidal™ leticonostoc/radish root fermentfiltrate as preservative. The amounts listed are the weight of thematerial as supplied. The Dermosoft™ 700B perfume can be included in anamount of 0.05 to 1 or 0.3 to 1 by weight of the composition (assupplied). The Leucidal™ leuconostoc/radish root ferment filtrate can beincluded in an amount of 0.2 to 2% by weight of the composition (assupplied). In one embodiment, Dermosoft™ 700B perfume is present in anamount of about 0.3 by weight (as supplied) of the composition and theLeucidal™ lenconostoc/radish root ferment filtrate is present at about1.25% by weight (as supplied) of the composition. The combinationprovides preservative protection against gram positive bacteria, grainnegative bacteria, mold, yeast, and fungus. The Leucidal™lenconostoc/radish root ferment filtrate is available from ActiveConcepts LLC, and the Dermosoft™ 700B is available from Dr. StraetmansChemische Produkte GmbH.

According to the MSDS for Dermosoft™ 700B, the material is about 40% byweight of a partially neutralized 4-oxovaleric acid, in glycerin andwater. When the composition is used at 0.05 to 1% by weight in acomposition, the active amount of 4-oxovaleric acid is 0.02 to 0.4 byweight.

In other embodiments, the Dermosoft™ 700B can be used alone, theLeucidal™ leuconostoc/radish root ferment filtrate can be used alone, orother preservatives can be used alone or in combination with thesepreservatives.

In another embodiment, the compositions can be opacified by including anopacifier, such as sunflower oil or Euperlan™ Green opacifier fromCognis (55-65% water, 15-25% lauryl glucoside and 15-25% stearylcitrate). The opacifier can be present in an amount of 1 to 5% by weightof the composition. In certain embodiments, the sunflower oil is presentat 1 to 5 or 2 to 4% by weight of the composition. In certainembodiments, the amount is about 3% by weight of the composition. Incertain embodiments, the Euperlan™ Green opacifier is present at 1 to 5or 2 to 4% by weight of the composition. In certain embodiments, theamount is about 3% by weight of the composition.

In certain embodiments, the cleansing composition can contain achelator. Examples of a chelator include, but are not limited to sodiumphytate and tetrasodium EDTA. In certain embodiments, the chelator ispresent in an amount of 0.001 to 3% by weight, 0.01 to 1:5% by weight,or 0.05 to 1.0% by weight of the composition.

In certain embodiments, the materials in the composition can be obtainedfrom naturally occurring sources that are sustainable. This provides acomposition that performs comparably to some anionic surfactant basedcleansing compositions yet is made from sources of raw materials thatare naturally occurring from sustainable sources.

The cleansing composition can be formulated to be in the form of ashower gel, body wash, liquid hand soap, or foaming, hand soap.

In some embodiments the pH of the composition is 2 to 9. In oneembodiment, the pH of the composition is 3 to 7. In other embodiments,the pH of the composition is 4 to 6. In another embodiment the pH of thecomposition is 6 to 8. The pH is measured at 25° C.,

In some embodiments, the composition has a Brookfield viscosity of 1 to25,000 mPas (cps). In one embodiment, the viscosity is less than 15,000mPas (cps). In other embodiments, the viscosity is 5000 to 12,000 mPas(cps). Brookfield viscosity is measured on a DVII viscometer withspindle 4 at 10 rpm at 25° C. In another embodiment the viscosity is 1to 100 mPas (cps) using spindle 3 at 100 rpm at 25° C.

Compositions may be made using conventional mixing techniques known tothose skilled in the art for mixing ingredients.

Specific Embodiments

The examples are merely illustrative and do not in any way limit thescope of the invention as described and claimed. In the examples below,all of the ingredients are obtained from a natural, sustainable source.

The following examples and comparative examples can be prepared bymixing of the ingredients. The amounts are in weight Water is added to avessel equipped with center turbine agitation. Citric acid (50%solution) is added to the water and mixed until homogeneous. Xanthan gumis slowly added to the water solution while mixing at high speed. Onceall the xanthan has been uniformly dispersed and the solution is clear,the decyl glucoside is slowly added to batch at medium speed untilhomogeneous. Coco-glucoside is added slowly to the batch at medium speedand mixed until homogeneous. Glycerin, salt, preservatives, and skinfeel enhancers (if necessary) are added to the batch in successionmixing until homogeneous in between components. pH and viscosity aremeasured and adjusted if necessary.

The following samples are prepared for testing by an expert panel. Thecompositions are compared against as body wash with anionic surfactantsavailable as Softsoap™ Pomegranate and Mango body wash fromColgate-Palmolive company. This comparative composition is about 13.7%sodium lauryl ether sulfate (70% active), about 5.7% cocoamidopropylbetaine, about 1% xanthan gum, with the balance being water,preservative, fragrance, and color.

Material Example 1 Example 2 Decyl glucoside 10 20 Plantaren ™ 2000 NUPCoco glucoside 5 10 Plantacare ™ 818 UP Xanthan gum 1.0 1.0 Glycerin 2.52.5 Sodium chloride 1.5 1.5 Dermosoft ™ 700B perfume (4-oxovaleric acid)0.6 0.6 (preservative) Water and minors, such as Q.S. Q.S. fragrance,color, pH adjustment Total 100 100

The compositions are evaluated by 9 expert panelists. Each panelistassesses each product using a standardized methodology and a 0-15 pointscale, 0 representing the none/low and 15 representing a high. Theexpert panel evaluates the products on sensory characteristicsincluding: Visual product appearance, foam evaluation on pouf and hand.

For visual evaluation, the panelist dispenses each test product from itsoriginal package using a 3-second consistent squeeze onto atransparency. The panelist then evaluates the test products on Integrityof Shape immediately and after 1 minute.

There are two phases of assessment on lather—lather generated on poufand lather generated on hands. The panelists evaluated such attributesas Amount of foam on pouf, firmness of foam and amount of foam on hands.For Pouf Evaluation Procedure, the panelist weighs 3.0 g±0.1 g onto atray. The panelist completely submerges the pouf in 33° C.±1 (92° F.±2)water for 5 seconds and then removes pouf. The panelist then adds theproduct from the tray onto the pouf, twists the pouf 10 times, and thenevaluates lather attributes. For Hand Evaluation Procedure, the panelistweighs out 2.0 g±0.1 g onto a tray. The panelist wets both hands underrunning water at 33° C.±1 (92° F.±2) for 5 seconds, then dispenses thetest product from the tray onto the non-dominant hand, and adds 2.5ml±0.1 ml of water. The panelist then uses a gentle circular motionrotating 10 times in the hand to generate lather and subsequentlyevaluates the lather attributes.

An analysis of variance (ANOVA) is performed on the panelists ratings ofproduct attributes; a within subject model was used. A Tukey HSD is usedto evaluate significant differences among the attributes (p<0.10; twotailed). The results from the expert panel are below.

10/5 20/10 Softsoap Prototype Prototype Pomegran- Example 1 Example 2ate P-value A B C VISUAL EVALUATION: Integrity <.0001 8.0 8.0 8.0 ofShape - Immediate Integrity <.0001 7.0 7.0 7.0 of Shape - 1 minute POUFEVALUATION: Amount of <.0001 4.4 4.2 4.2 Foam-5T Amount of <.0001 9.0 BC8.2 A 8.3 A Foam-10T Firmness of <.0001 2.1 B 1.6 A 2.0 B Foam-10T HANDEVALUATION: Amt Foam- <.0001 2.0 1.9 2.0 Hands-5T Amt Foam- 0.0022 4.03.9 4.0 Hands-10T

It can be seen that the glucoside containing compositions performsimilarly to the anionic containing surfactant composition.

The formulas below are for opacified versions of Examples 1 and 2.

Material Example 3 Example 4 Decyl glucoside 10 20 Plantaren ™ 2000 NUPCoco glucoside 5 10 Plantacare ™ 818 UP Xanthan gum 1.0 1.0 Glycerin 2.52.5 Sodium chloride 1.5 1.5 Dermosoft ™ 700B perfume (4-oxovaleric acid)0.6 0.6 (preservative) Sunflower oil (opacifier) 3 3 Water and minors,such as fragrance, color, Q.S. Q.S. pH adjustment Total 100 100The formula below is for a foaming liquid hand soap.

Material Example 5 Decyl Glucoside 10 Coco Glucoside 5 Dermosoft ™ 700Bperfume (4-oxovaleric acid) 0.3 (preservative) Leucidal ™leuconostoc/radish root 1.25 ferment filtrate (preservative) Water andminors, such as Q.S. fragrance, color, pH adjustment Total 100

Below is a prophetic example.

Material Ex. 6 Decyl glucoside:coco glucoside ratio 2:1 Decyl glucoside10-20 Plantaren ™ 2000 NUP Coco glucoside  5-10 Plantacare ™ 818 UPXanthan gum   1-1.25 Glycerin 3 Sodium chloride 1.5 Dermosoft ™ 700Bperfume (4-oxovaleric acid) 0.3 (preservative) Leucidal ™leuconostoc/radish root 1.25 ferment filtrate (preservative) Water andminors, such as Q.S. fragrance, color, pH adjustment Total 100

What is claimed is:
 1. A cleansing composition comprising: a) apartially neutralized 4-oxovaleric acid present in an amount of 0.02 to0.4% by weight of the composition, b) leuconostoc/radish root fermentfiltrate present in an amount of 0.2 to 2% by weight of the composition,wherein the leuconostoc/radish root ferment filtrate is derived fromradishes fermented with Leuconostoc kimchii, a lactic acid bacteria, c)at least one surfactant present in an amount of 1 to 45% by weight ofthe composition, and d) water, wherein the combination of the partiallyneutralized 4-oxovaleric acid and leuconostoc/radish root fermentfiltrate provides preservative protection against gram positivebacteria, gram negative bacteria, mold, yeast and fungus.
 2. Thecleansing composition of claim 1, wherein the partially neutralized4-oxovaleric acid is present in an amount of about 0.12% by weight ofthe composition and the leuconostoc/radish root ferment filtrate ispresent at about 1.25% by weight of the composition.
 3. The cleansingcomposition of claim 1, wherein the at least one surfactant is free ofan anionic surfactant.
 4. The cleansing composition of claim 1, whereinthe at least one surfactant comprises a combination of decyl glucosideand coco glucoside.
 5. The cleansing composition of claim 1, furthercomprising at least one of a thickener and an opacifying agent.
 6. Thecleansing composition of claim 5, wherein the opacifying agent issunflower oil or a composition comprising 55-65% water, 15-25% laurylglucoside and 15-25% stearyl citrate.
 7. The cleansing composition ofclaim 6, wherein the opacifying agent is present in an amount of 1 to 5%by weight of the composition.
 8. The cleansing composition of claim 1,further comprising a chelator.
 9. The cleansing composition of claim 8,wherein the chelator is sodium phytate or tetrasodium EDTA.
 10. Thecleansing composition of claim 8, wherein the chelator is present in anamount of 0.001 to 3%.
 11. The cleansing composition of claim 4, furthercomprising a chelator.
 12. The cleansing composition of claim 1, furthercomprising a chelator, a thickener and an opacifying agent.
 13. Thecleansing composition of claim 12, wherein the opacifying agent issunflower oil or a composition comprising 55-65% water, 15-25% laurylglucoside and 15-25% stearyl citrate, wherein the opacifying agent ispresent in an amount of 1 to 5% by weight of the composition, whereinthe chelator is sodium phytate or tetrasodium EDTA, and wherein thechelator is present in an amount of 0.001 to 3%.
 14. The cleansingcomposition of claim 1, wherein the cleansing composition is in the formof a shower gel, body wash, liquid hand soap, or foaming, hand soap.